The SARS-CoV-2 spike (S) and the orthoreovirus p15 cause neuronal and glial fusion
Ramón Martínez‐Mármol, Rosina Giordano-Santini, Eva Kaulich, Ann‐Na Cho, Magdalena Przybyla, M. Asrafuzzaman Riyadh, Emilija Robinson, Keng Yih Chew, Rumelo Amor, Frédéric A. Meunier, Giuseppe Balistreri, Kirsty Renfree Short, Yazi Diana Ke, Lars Matthias Ittner, Massimo A. Hilliard
This study shows that SARS-CoV-2 spike and orthoreovirus p15 proteins induce fusion between neurons and glial cells across species, leading to syncytia and organelle exchange.
Science Advances · Jun 7, 2023Peer-reviewedNeuroscience