Massimo A. Hilliard

This study identifies AGEF-1a as a conserved Arf-GEF that maintains axonal integrity by modulating RAB-35 activity in neuron-epidermal attachments in C. elegans.

The paper identifies a neuron-specific quality-control compartment, SolAS, that sequesters and expels misfolded proteins, showing its role in proteostasis during aging.

This study shows that SARS-CoV-2 spike and orthoreovirus p15 proteins induce fusion between neurons and glial cells across species, leading to syncytia and organelle exchange.

The paper shows that spectrin forms a periodic scaffold in the epidermis that protects axons from mechanical damage during development and regeneration.

This study identifies RAB-5 as a regulator of axonal fusion in C. elegans by controlling EFF-1 endocytosis, showing that perturbing RAB-5 enhances fusion capacity.

The paper identifies TTR-33 as a neuroprotective factor against 6-OHDA-induced dopaminergic neurodegeneration in C. elegans, showing its role in oxidative stress resistance and interaction with MAPK pathways.