Andrzej S. Kudlicki

The paper resolves geometric inconsistencies in Hi-C data by modeling the sample as a mixture of chromatin conformation states, showing that 4-5 subpopulations can resolve most spatial conflicts.

The paper modifies Direct Coupling Analysis to predict interaction domains in large protein complexes, validated on known and unknown complexes.

The paper identifies functional interactions between 5-HT2A and 5-HT2C receptors using coevolution analysis and finds significant correlations between predicted binding interfaces and SNPs in these proteins.

The paper estimates genome-wide protein abundances and dynamics from gene expression data without assuming steady-state conditions, validated using yeast cell cycle data.