The paper shows TYLCV co-opts its vector's m6A machinery to enhance reproductive fitness in resistant whiteflies, revealing a mechanism for adaptive virus-vector interactions.

bioRxiv · Aug 27, 2026 · PreprintMicrobiology

RNA m6A demethylase ALKBH4 governs whitefly development

Jing Yang, Chao Wang, Peipan Gong, Chao He, Buli Fu, Shaonan Liu, Xuegao Wei, Cheng Yin, Mingjiao Huang, Tianhua Du, Jinjin Liang, Xuguo Joe Zhou, Ralf Nauen, Youjun Zhang, Chris Bass, Xin Yang

This study identifies ALKBH4 as an m6A demethylase in whiteflies, showing its role in reversing mRNA methylation and regulating development.

bioRxiv · Aug 10, 2026 · PreprintZoology

A horizontally transferred fungal deubiquitinase facilitates insecticides resistance in whitefly

Hantang Lu, C H I Zhang, Jinyu Hu, C Y Wang, Rong Zhang, Mingjiao Huang, 谭启梅, Cheng Yin, Jixing Xia, Wu Yidong, Xuguo Joe Zhou, Ralf Nauen, Y ZHANG, Chris Bass, Xin Yang

This study identifies a horizontally transferred fungal deubiquitinase, BtUCH19, that enhances insecticide resistance in whiteflies by stabilizing a detoxification enzyme through ubiquitin modification.

bioRxiv · Jun 4, 2026 · PreprintZoology

Nanopore Sequencing Unveils Somatic Structural Variations as Biomarkers in Laryngeal squamous cell carcinoma Genomes

Xuyan Liu, Lin Xia, Yixin Qiao, Yang Li, Yan Huang, Bing Yue, Xi Liang, Xin Yang, Honghui Zhang, Jiaxun Zhang, Xiao Chen, Dan Xie, Jifeng Liu

This study introduces SomaGauss-SV, a nanopore-based method for detecting somatic structural variations in LSCC, revealing correlations with smoking and gene expression.

bioRxiv · Jun 12, 2025 · PreprintBioinformatics