Author

Luke N. Yaeger

Michael G. DeGroote Institute for Infectious Disease ResearchORCID 0000-0001-8179-8330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hanjeong Harvey· 2 shared Lori L. BurrowsiD· 2 shared Michael R. M. Ranieri· 2 shared Alessio M. Giovannoni· 1 shared Annamaria Dobrin· 1 shared David SychanthaiD· 1 shared George Colin diCenzoiD· 1 shared Jakob MagolaniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Hanjeong Harvey

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedJan 29, 2025

Metabolic connections between folate and peptidoglycan pathways in Pseudomonas aeruginosa inform rational design of a dual-action inhibitor

Luke N. Yaeger, David Sychantha, Princeton Luong…·Lori L. Burrows

This study identifies metabolic links between folate and peptidoglycan pathways in Pseudomonas aeruginosa and uses these insights to design a dual-action inhibitor that overcomes antibiotic resistance.

12 citations

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 5, 2023

A genetic screen identifies a role for oprF in Pseudomonas aeruginosa biofilm stimulation by subinhibitory antibiotics

Luke N. Yaeger, Michael R. M. Ranieri, Jessica Chee…·Lori L. Burrows

This paper identifies OprF and SigX as key factors in sub-MIC antibiotic-induced biofilm formation in Pseudomonas aeruginosa, linking periplasmic redox changes to c-di-GMP signaling.

DOI 10.1101/2023.09.05.556382

bacteria (other)genetic perturbation / CRISPR

𝕏 PostBluesky