Matthew J. Meier

The paper introduces a statistical framework to analyze mutation spectra in error-corrected sequencing data, showing it maintains Type I error control and greater power than existing methods.

This study assesses the mutagenic and clastogenic effects of benzo[b]fluoranthene in mice using Duplex Sequencing and the micronucleus assay, showing dose-dependent increases in mutation frequency and cancer-related mutation spectra.

This study uses Duplex Sequencing to assess mutation frequencies and spectra in MutaMouse bone marrow after procarbazine exposure, showing its advantages over conventional assays.