Danielle P. M. LeBlanc

The paper introduces a statistical framework to analyze mutation spectra in error-corrected sequencing data, showing it maintains Type I error control and greater power than existing methods.

This study assesses the mutagenic and clastogenic effects of benzo[b]fluoranthene in mice using Duplex Sequencing and the micronucleus assay, showing dose-dependent increases in mutation frequency and cancer-related mutation spectra.

This study uses Duplex Sequencing to assess mutation frequencies and spectra in MutaMouse bone marrow after procarbazine exposure, showing its advantages over conventional assays.

This study examines how folic acid deficiency and supplementation affect mutation rates in bone marrow and colon, revealing tissue-specific mutagenic effects.