Author

María Alejandra Castilla Bolaños

University of TorontoORCID 0000-0001-8204-4610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

André J. SimpsoniD· 1 shared Carol SchuurmansiD· 1 shared Colleen BaileyiD· 1 shared Fermisk SalehiD· 1 shared Jamie NeariD· 1 shared Laura Bustamante-Paredes· 1 shared Maggie Wu· 1 shared Mariana Duenas-Rodriguez· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

André J. SimpsonORCID

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2 papers

Recent·Most cited

BiophysicsNMR in BiomedicinePeer-reviewedJun 26, 2026

Metabolic analysis in intact human-derived cerebral organoids by high-resolution magic-angle spinning NMR spectroscopy

María Alejandra Castilla Bolaños, Vorapin Chinchalongporn, Rajshree Ghosh Biswas…·Jamie Near

This study uses HR-MAS NMR to analyze metabolism in human-derived cerebral organoids at different developmental stages, finding a metabolic profile similar to the human brain with some differences.

4 citationstop 3%

humanmetabolomics

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Pharmacology & ToxicologybioRxivPreprintFeb 18, 2025

Fabrication & characterization of hyaluronic acid/eucalyptus hydrogels loaded with PLGA nanoparticles with methotrexate as an Injectable therapy for rheumatoid arthritis

María Alejandra Castilla Bolaños, Mariana Duenas-Rodriguez, Laura Bustamante-Paredes, Samuel Castillo-Heins

This study develops hyaluronic acid/eucalyptus hydrogels loaded with PLGA nanoparticles containing methotrexate as an injectable therapy for rheumatoid arthritis, showing improved stability and biocompatibility.

1 citation

experimental assaydrug response / drug discovery

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