Jamie Near

The paper describes the development of a harmonized multisite MRI protocol for pediatric brain imaging and validates its cross-site consistency.

This study uses HR-MAS NMR to analyze metabolism in human-derived cerebral organoids at different developmental stages, finding a metabolic profile similar to the human brain with some differences.

This study benchmarks how different anatomical segmentation tools affect MRS-derived metabolite concentration estimates in brain imaging.

MRS4Brain provides a MATLAB-based toolbox for preclinical MR spectroscopy and imaging, streamlining data processing and improving reproducibility and accessibility.

The paper identifies NEUROG2's role in regulating a human-specific gene regulatory program in neural progenitor cells through transcriptomic analysis of knock-in organoids.

This study assesses white matter hyperintensity severity using multimodal MRI in Alzheimer's Disease by analyzing signal measures from different MRI contrasts and their associations with clinical variables.

The paper compares seven algorithms for modelling GABA-edited 1H-MRS data from 222 subjects across 20 sites, finding moderate agreement and highlighting the need for standardized parameters.

This study examines neuroanatomical changes in Fischer 344 rats during aging and between sexes using longitudinal MRI, identifying age- and sex-related differences in brain regions associated with memory and motor control.

The paper shows that MRS-measured Glutamate and GABA levels in awake mice correlate with excitatory and inhibitory neural activities during stimulation and in a Dravet syndrome model.

This study examines the impact of MRI scanner upgrades and volumetric navigators on structural and spectroscopy indices, finding mixed reliability and changes in brain measurements.

This study quantifies metabolites and macromolecules in aging Fischer 344 rats using MRI, revealing age- and sex-related changes in brain chemistry associated with healthy aging.

The paper develops a high-resolution MRI atlas of the Fischer 344 rat brain, including 71 segmented regions and analysis of sex differences in brain volume.