Author

Talha Shafi

University of YorkORCID 0000-0001-8214-2579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Andrzej Marek BrzozowskiiD· 1 shared Huw T. JenkinsiD· 1 shared Jiřı́ JiráčekiD· 1 shared Maria ChechikiD· 1 shared Marta LubosiD· 1 shared Michail N. Iusupov· 1 shared Olga V. MoroziD· 1 shared Pierre DE MEYTSiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Andrzej Marek BrzozowskiORCID

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1 paper

Recent·Most cited

BiochemistryOpen BiologyPeer-reviewedJun 17, 2026

Structural basis of Drosophila insulin receptor activation by DILP2 hormone

Talha Shafi, Olga V. Moroz, Huw T. Jenkins…·Andrzej Marek Brzozowski

This study presents two cryo-EM structures of the Drosophila insulin receptor ectodomain bound to DILP2, revealing structural and kinetic differences in hormone binding.

DOI 10.1098/rsob.250351

Drosophilastructural biology

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