Author

İhsan Ekin Demir

Technical University of MunichORCID 0000-0001-8241-1871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Alexandra BerningeriD· 1 shared Bojana GligorijeviciD· 1 shared Boris RevaiD· 1 shared Bruno SáinziD· 1 shared C. Dai· 1 shared Chun-Hao Chen· 1 shared D. Bakırdöğen· 1 shared Deniz DemircioğluiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Alexandra BerningerORCID

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3 papers

Recent·Most cited

Cancer BiologyGutPeer-reviewedJun 23, 2026

Pancreatic cancer fibrosis activates protumorigenic Schwann cells through a nuclear mechanosensing mechanism.

Pavel Stupakov, Golbahar Sadatrezaei, Ines Velazquez Quesada…·Sylvie Deborde

This study identifies a mechanism by which pancreatic fibrosis activates protumorigenic Schwann cells through nuclear mechanosensing involving c-Jun phosphorylation and Phospholipase A2.

5 citationstop 1%

humanbulk RNA-seq

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Cancer BiologyMolecular CancerPeer-reviewedDec 15, 2025

c-Rel drives pancreatic cancer metastasis through Fibronectin-Integrin signaling-induced isolation stress resistance and EMT activation

D. Bakırdöğen, Kıvanç Görgülü, J. Xin…·Hana Algül

This study identifies c-Rel as a driver of pancreatic cancer metastasis by promoting EMT, ECM remodeling, and resistance to isolation stress through fibronectin-integrin signaling.

6 citations

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 13, 2025

Transcriptomic Analysis Of The Relationship Between Pancreatic Ductal Adenocarcinoma Stromal Subtypes And Neural Invasion

Saliha Elif Yıldızhan, İhsan Ekin Demir, Elif Arik Sever…·Guralp Onur Ceyhan

The paper investigates the relationship between PDAC stromal subtypes and neural invasion using single-sample classifiers and RNA-seq data, finding activated stroma is enriched in neuro-invasive samples.

DOI 10.1101/2025.01.13.632859

humanbulk RNA-seq

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