RNA polymerase II-mediated rDNA transcription mediates rDNA copy number expansion in Drosophila
George J. Watase, Yukiko M Yamashita
The paper identifies Indra as a negative regulator of rDNA copy number expansion in Drosophila by repressing RNA polymerase II-mediated rDNA transcription, which facilitates rDNA magnification through retrotransposon activity.