Megan E. Doty

The paper shows that microglial processes involved in surveillance, chemotaxis, and phagocytosis lack mitochondria, while mitochondria arrive later in response to damage.

The paper integrates metabolomic, proteomic, and phospho-proteomic analyses of dorsal root ganglia from DPN donors and controls to identify molecular changes associated with diabetic neuropathic pain.

The paper identifies 844 differentially expressed genes in DRGs from DPN patients, showing increased inflammation and decreased neuronal genes, suggesting intraganglionic pathology in diabetic neuropathy.