Author

Daniel Holmes

Michigan State UniversityORCID 0000-0001-8275-9237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Assaf A. GiladiD· 1 shared Björn HambergeriD· 1 shared Debkumar DebnathiD· 1 shared Emily R. LanieriD· 1 shared Iliya MiralavyiD· 1 shared Jayasubba Reddy YaravaiD· 1 shared Julia BroseiD· 1 shared Li Xie· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiophysics

Assaf A. GiladORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Machine learning-based development of Gadolinium binding peptides

Nir A. Dayan, Makayla Long, Nicolas Scalzitti, Iliya Miralavy, Daniel Holmes, Mark Kocherovsky, Wolfgang Banzhaf, Assaf A. Gilad

This paper uses machine learning to design Gd-binding peptides with improved relaxivity and specificity for MRI contrast agents.

NMR in Biomedicine · Sep 11, 2026Peer-reviewedBiophysics

Rapid High-Resolution Analysis of Polysaccharide-Lignin Interactions via Proton-Detected Solid-State NMR with Application to Eucalyptus and Spruce

Peng Xiao, Jayasubba Reddy Yarava, Debkumar Debnath, Priya Sahu, Yifan Xu, Li Xie, Daniel Holmes, Tuo Wang

This study uses 1H-detected solid-state NMR to rapidly analyze polysaccharide-lignin interactions in eucalyptus and spruce, revealing new structural insights without solubilization.

Analytical Chemistry · Aug 15, 2025Peer-reviewedBiophysics

CYP76BK1 orthologs catalyze furan and lactone ring formation in clerodane diterpenoids across the mint family

Nicholas Schlecht, Emily R. Lanier, Trine Bundgaard Andersen, Julia Brose, Daniel Holmes, Björn Hamberger

This paper identifies and functionally characterizes CYP76BK1 orthologs across Lamiaceae subfamilies, showing their role in furanoclerodane biosynthesis and evolutionary conservation.

The Plant Journal · Sep 14, 2024Peer-reviewedPlant Biology