Author

Li Xie

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Ecology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Tuo WangiD· 3 shared Ankur AnkuriD· 2 shared Jayasubba Reddy YaravaiD· 2 shared A. Ercument Cicek· 1 shared Aaron Topol· 1 shared Andrew Browne· 1 shared Andrew Chess· 1 shared Babak Momeni· 1 shared

Activity by Year

2016-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiochemistry

Tuo WangORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Molecular Architecture of Cryptococcus Cell Walls Reveals Species-Specific Chitosan-Dependent Remodeling

Ankur Ankur, Rajendra Upadhya, Mahsa Doosti, Davis Fernandes Ferreira, Li Xie, Ivan Hung, Jennifer Lodge, Tuo Wang

This study examines the structural role of chitosan in Cryptococcus cell walls, revealing species-specific remodeling effects when chitosan is absent.

bioRxiv · Apr 15, 2026 · PreprintBiochemistry

Rapid High-Resolution Analysis of Polysaccharide-Lignin Interactions via Proton-Detected Solid-State NMR with Application to Eucalyptus and Spruce

Peng Xiao, Jayasubba Reddy Yarava, Debkumar Debnath, Priya Sahu, Yifan Xu, Li Xie, Daniel Holmes, Tuo Wang

This study uses 1H-detected solid-state NMR to rapidly analyze polysaccharide-lignin interactions in eucalyptus and spruce, revealing new structural insights without solubilization.

Analytical Chemistry · Aug 15, 2025Peer-reviewedBiophysics

Polymorphic α-Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights from 13C and 1H Solid-State NMR

Ankur Ankur, Jayasubba Reddy Yarava, Isha Gautam, Faith J. Scott, Frédéric Mentink‐Vigier, Christine Chrissian, Li Xie, Dibakar Roy, Ruth E. Stark, Tamara Lea Doering, Ping Wang, Tuo Wang

This study uses solid-state NMR to reveal five structural forms of α-glucans in Cryptococcus cell walls, showing their role in scaffolding and interacting with chitin, capsule, and melanin.

Angewandte Chemie International Edition · Jul 8, 2025Peer-reviewedBiochemistry

The validity of pairwise models in predicting community dynamics

Babak Momeni, Li Xie, Wenying Shou

This study evaluates the validity of pairwise models in predicting microbial community dynamics, showing that incorrect models can lead to wrong predictions when interactions involve consumable or reusable mediators.

bioRxiv · Aug 27, 2016Ecology

Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

Menachem Fromer, Panos Roussos, Solveig K Sieberts, Jessica S Johnson, David H Kavanagh, Thanneer M Perumal, Douglas M Ruderfer, Edwin C Oh, Aaron Topol, Hardik R Shah, Lambertus L Klei, Robin Kramer, Dalila Pinto, Zeynep H Gumus, A. Ercument Cicek, , Lara M Mangravit

The paper uses gene expression data from schizophrenia cases and controls to show that common variants at 20% of schizophrenia risk loci regulate brain gene expression, with functional impacts on neural progenitor cells and zebrafish neuroanatomy.

bioRxiv · May 9, 2016Genomics

The Plasmodium falciparum drugome and its polypharmacological implications

Yinliang Zhang, Li Xie, Lei Xie, Philip E. Bourne

The paper maps FDA drugs to Plasmodium falciparum targets to identify potential new anti-malaria candidates and multi-target therapeutics.

bioRxiv · Mar 5, 2016 · PreprintSystems Biology