Author

Danyang Wan

National Institutes of HealthORCID 0000-0001-8278-3616Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ji‐Eun LeeiD· 2 shared Kai GeiD· 2 shared Oksana GavrilovaiD· 2 shared Young-Kwon ParkiD· 2 shared Christabelle AgyapongiD· 1 shared Guojia XieiD· 1 shared Keiko OzatoiD· 1 shared Nhien TraniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

Ji‐Eun LeeORCID

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2 papers

Recent·Most cited

PhysiologyProceedings of the National Academy of SciencesPeer-reviewedJul 6, 2026

Histone Chaperone HIRA regulates adiponectin expression and obesity-associated adipose expansion by facilitating Pol II pause release

Danyang Wan, Ji‐Eun Lee, Young-Kwon Park…·Kai Ge

This study identifies HIRA as an epigenomic regulator of adipose tissue function, showing it promotes adiponectin and lipid metabolism gene expression by facilitating RNA polymerase II pause release.

1 citation

mouseChIP-seq

𝕏 PostBluesky

Developmental BiologyGenes & DevelopmentPeer-reviewedApr 22, 2021

MED1 is a lipogenesis coactivator required for postnatal adipose expansion

Younghoon Jang, Young-Kwon Park, Ji‐Eun Lee…·Kai Ge

This study shows MED1 is essential for postnatal adipose expansion and de novo lipogenesis gene induction in mice, but not for adipose development or early adipogenesis.

22 citations

mousebulk RNA-seq

𝕏 PostBluesky