Molecular BiologyNature CommunicationsPeer-reviewed
A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2
Yingna Xu, Wenbo Feng, Qingtong Zhou…·Ming‐Wei Wang
This study reports the cryo-EM structure of the human VIP2R bound to PACAP27 and Gs, revealing a unique N-terminal helix conformation that stabilizes the ligand-receptor interface.
20 citations