Targeting Mitochondrial Dysfunction with Mdivi-1 Confers Therapeutic Protection in a Mouse Model of Mustard Keratopathy
Arpan G. Mazumder, Evan Magarychoff, Hamid Alemi, Rahul Raghav, Michael T. Chin, Zhen Yan, Christopher D. Wiley, M. Elizabeth Fini
This study identifies mitochondrial dysfunction as a key mechanism in mustard keratopathy and shows that inhibiting DNM1L with Mdivi-1 protects against corneal injury in mice.
bioRxiv · Sep 2, 2026 · PreprintMolecular Biology