Daniel J. Wiegand

The paper develops an aqueous-based enzymatic platform for template-independent RNA oligonucleotide synthesis, demonstrating compatibility with therapeutic modifications and offering a sustainable alternative to chemical methods.

The paper demonstrates a single-molecule method to screen polymerase variants using nanopore sequencing and barcoding, enabling multiplexed analysis of kinetic properties.

This paper introduces a method to store digital data in DNA using enzymatic synthesis guided by light patterns, demonstrating storage of 110 bits of data.

This paper develops a cell-free expression system using Vibrio natriegens, achieving high protein yield through optimized culturing and extract preparation.