GeneticsScience AdvancesPeer-reviewed
Pervasive head-to-tail insertions of DNA templates mask desired CRISPR/Cas9-mediated genome editing events
Boris V. Skryabin, Delf-Magnus Kummerfeld, Leonid Gubar…·Timofey S. Rozhdestvensky
The paper identifies head-to-tail DNA template insertions in CRISPR/Cas9 editing and highlights the failure of PCR to detect them, advocating for comprehensive analysis.
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