Comparing the transmission blocking efficacy of Primaquine and Tafenoquine with in vivo pre-clinical models
Maëlle Duffey, Sara E. Zakutansky, Christin Gumpp, Michael J. Delves, Katarzyna A Sala, Ellie Sherrard-Smith, Jake Baum, Didier Leroy, Matthias Rottmann, Andrew M. Blagborough
This study compares the transmission blocking efficacy of primaquine and tafenoquine in vivo, finding tafenoquine more effective due to better pharmacokinetics beyond 24 hours.
bioRxiv · Mar 3, 2026 · PreprintMicrobiology