Anastasia Hernández-Koutoucheva

Genomic connectivity and the spread of adaptive insecticide resistance alleles in Anopheles arabiensis from East Africa

This study uses whole-genome sequencing to analyze genomic connectivity and adaptive gene flow of insecticide resistance alleles in Anopheles arabiensis across East Africa, revealing transboundary spread despite geographic barriers.

Genomic signatures of selection in Anopheles funestus reveal shared and population-specific adaptive variation across African populations

The paper identifies genomic signatures of selection in Anopheles funestus across African populations, revealing shared and population-specific adaptive variation linked to insecticide resistance and neuromodulatory pathways.

Genetic Surveillance Reveals Differential Evolutionary Dynamic of Anopheles gambiae Under Contrasting Insecticidal Tools used in Malaria control

This study uses genomic data to analyze evolutionary dynamics of Anopheles gambiae under different insecticidal tools, revealing distinct resistance mechanisms and allele frequency shifts.

Signatures of selection and mechanisms of insecticide resistance in Ugandan Anopheles funestus: Insights from embedding translational genomics into the LLINEUP cluster randomised trial.

This paper uses genomic surveillance in a cluster randomized trial to detect insecticide resistance variants in Ugandan Anopheles funestus and An. gambiae s.l., showing differential population responses to pyrethroid and PBO interventions.

The origin, invasion history and resistance architecture of Anopheles stephensi in Africa.

This study traces the origin and spread of Anopheles stephensi in Africa using genomic data and identifies insecticide resistance genes from Asia.

Targeted genomic surveillance of insecticide resistance in African malaria vectors

This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.

Distinct Genetic Populations and Resistance Backgrounds of the Malaria Vector Anopheles funestus in Tanzania

The paper analyzes the population genetics of Anopheles funestus in Tanzania, identifying two distinct genetic populations with different resistance backgrounds and suggesting geographic barriers to gene flow.

Discovery of knock-down resistance in the major malaria vector Anopheles funestus.

The paper discovers knock-down resistance (kdr) mutations in Anopheles funestus, a major malaria vector, showing resistance to DDT but not deltamethrin.