Tristan P. W. Dennis

A genomic toolkit for surveillance and elimination of the principal malaria vectors in Southeast Asia.

The paper provides genomic resources for malaria vector surveillance in Southeast Asia, revealing population structure and resistance regions in Anopheles dirus.

Must epidemiologically impactful vector control interventions disrupt mosquito population structure? A case study of a cluster-randomised controlled trial.

This study analyzes genetic data from a mosquito control trial to assess if vector control impacts population structure, finding no significant genetic changes despite reduced vector density.

Prevalence of zoonotic hepatic nematode varies with small mammal community diversity across a heterogenous landscape in Eastern Uganda

This study finds higher prevalence of Calodium hepatica in areas with lower small mammal diversity, particularly linked to increased Rattus rattus presence in Eastern Uganda.

The origin, invasion history and resistance architecture of Anopheles stephensi in Africa.

This study traces the origin and spread of Anopheles stephensi in Africa using genomic data and identifies insecticide resistance genes from Asia.

Distinct Genetic Populations and Resistance Backgrounds of the Malaria Vector Anopheles funestus in Tanzania

The paper analyzes the population genetics of Anopheles funestus in Tanzania, identifying two distinct genetic populations with different resistance backgrounds and suggesting geographic barriers to gene flow.

A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus 'fossil record'.

The paper introduces a database-integrated genome screening approach to explore the dark genome, identifying over 1.1 million endogenous viral elements across 874 vertebrate species.

Discovery of knock-down resistance in the major malaria vector Anopheles funestus.

The paper discovers knock-down resistance (kdr) mutations in Anopheles funestus, a major malaria vector, showing resistance to DDT but not deltamethrin.

Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

The paper investigates insecticide resistance and population structure in Anopheles gambiae from southern DRC, finding high resistance and genetic differentiation between populations.

Estimating the number of breeders from helminth larvae with genomic data.

The paper estimates the number of adult helminth worms using genomic data from larvae to distinguish between treatment success and reinfection.

Target-enrichment sequencing yields valuable genomic data for difficult-to-culture bacteria of public health importance

This study evaluates target-enrichment sequencing for generating genomic data from difficult-to-culture bacteria, showing it can produce high-quality data with sufficient coverage for variant calling.

Population genomics of Bacillus anthracis from an anthrax hyperendemic area reveals transmission processes across spatial scales and unexpected within-host diversity

This study analyzes the population genomics of Bacillus anthracis in Tanzania, revealing unexpected within-host diversity and transmission patterns influenced by livestock movements.

Database-integrated genome screening (DIGS): exploring genomes heuristically using sequence similarity search tools and a relational database.

The paper introduces a computational framework called DIGS for systematically screening genomes using sequence similarity search tools and a relational database, demonstrating its application in identifying novel endogenous viral elements in mammalian genomes.