Kylie P. Glanville

This paper uses genetic data to support cardiorespiratory fitness (CRF) as a clinical vital sign and advocates for routine physical activity prescription in healthcare.

This study investigates how genetic factors vary with different components of major depressive disorder using UK Biobank data, finding that symptom count and duration significantly affect heritability.

This study evaluates polygenic scoring methods in a reference-standardized framework, finding that LDPred2, lassosum, and PRScs provide the best predictive performance.

This study evaluates gene expression risk scores (GeRS) for predicting neuropsychiatric and anthropometric traits, finding they improve prediction when combined with polygenic risk scores (PRS).

This study uses multiple depression measures to improve the validity of Major Depressive Disorder cases in the UK Biobank, finding increased genetic contribution with more measures.

This study uses polygenic risk scores for major depression to examine the continuous nature of depressive symptoms across a large UK Biobank sample.

The paper examines phenotypic and genetic relationships between cannabis use, depression, and self-harm using UK Biobank and consortium data, finding associations and genetic correlations.

This study uses family-based genetic effects to estimate heritability of neuroticism and education in the UK Biobank, finding increased heritability and couple environmental influence on education.

The paper identifies a genetic subgroup within depression linked to age of natural menopause using UK Biobank data, but finds no replication in other cohorts.

This study investigates whether genetic variation in the Major Histocompatibility Complex (MHC) is associated with depression risk, finding no significant associations at a conservative threshold.

This study examines the association between schizophrenia polygenic risk scores and 420 behavioural traits in the UK Biobank, identifying potential causal pathways and highlighting the need for further research.