Zhendong A. Zhong

This study shows that deleting Znrf3 in osteoblasts reduces trabecular bone mass and alters cortical bone structure, while Rnf43 deletion has minimal effects.

This study identifies FZD6 as a key driver of EMT and stromal remodeling in basal-like pancreatic cancer, downstream of SP1, with implications for therapeutic targeting.

This paper models a human FZD2 variant in mice, identifies limb and cleft palate phenotypes, and shows DKK1 inhibition can normalize limb defects.