Author

Payton D. Stevens

Van Andel Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bart O. WilliamsiD· 2 shared Cassandra R. DiegeliD· 2 shared Aaron Honabarger· 1 shared Abigail G. Branch· 1 shared Catriona S. Giannotta· 1 shared Daniel Dick· 1 shared David Arthur TuvesoniD· 1 shared Elliott B. BurdetteiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Bart O. WilliamsORCID

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Author profile →

3 papers

Recent·Most cited

Frizzled 6 Drives EMT and Stromal Remodeling Downstream of SP1 in Basal-like Pancreatic Cancer

Payton D. Stevens, Catriona S. Giannotta, Evan Spires, Cassandra R. Diegel, Zhendong A. Zhong, Zachary Madaj, Samuel Isaac Olson, Mohamed H. Dawood, Aaron Honabarger, Giuseppina Caligiuri, David Arthur Tuveson, Galen H. Hostetter, Bart O. Williams

This study identifies FZD6 as a key driver of EMT and stromal remodeling in basal-like pancreatic cancer, downstream of SP1, with implications for therapeutic targeting.

bioRxiv · Jan 1, 2026 · PreprintCancer Biology

Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal Adenocarcinoma

Pritha Adhikary, Jayati L. Chakrabarti, Saptarshi Mallick, Xi Sun, Ugonna Ezuma-Igwe, Abigail G. Branch, Jiang Wang, Nicolas Braissand, Megan P. Corbett, Sangmin Kim, Rohan Kanakamedala, Willian C. Bastian, Eugene Douglass, Meenu Priya Resmi, Payton D. Stevens, , Yana L. Zavros

The paper uses spatial imaging and organoid models to identify therapy-resistant CD44v9+ cancer stem cells in PDAC and show that cabozantinib may enhance immunotherapy by altering the tumor microenvironment.

bioRxiv · May 22, 2025 · PreprintCancer Biology

Mutation of the Galectin-3 Glycan Binding Domain (Lgals3-R200S) Enhances Cortical Bone Expansion in Male and Trabecular Bone Mass in Female Mice

Kevin A. Maupin, Cassandra R. Diegel, Payton D. Stevens, Daniel Dick, VAI Vivarium and Transgenic Core, Bart O. Williams

This study shows that the Lgals3-R200S mutation in mice reduces galectin-3 secretion and alters bone mass differently in males and females.

FEBS Open Bio · Sep 5, 2022Peer-reviewedDevelopmental Biology