Lennart Enders

Continuous transcriptome analysis reveals novel patterns of early gene expression in Drosophila embryos.

This paper presents a single-embryo RNA-sequencing method to analyze early Drosophila gene expression, revealing transcription start times, degradation patterns, and sex-biased transcription.

Intergenerational metabolic priming by sperm piRNAs

This study shows that paternal dietary sugar affects offspring gene expression through sperm piRNA pathways, linking small RNA regulation to intergenerational epigenetic inheritance.

The Polycomb-dependent epigenome controls β-cell dysfunction, dedifferentiation and diabetes

This study identifies chromatin-state signatures linked to β-cell dysfunction and diabetes by combining epigenome mapping with single-cell transcriptomics in mice and humans.