Kin H. Lau

The paper investigates how G2019S LRRK2 interacts with metabolic syndrome in a mouse model of Parkinson's disease, showing systemic nucleotide and energy metabolism disruptions and mitochondrial dysfunction.

This study shows that KATANIN, encoded by two genes in maize, promotes cell elongation and division by affecting microtubule severing, PPB formation, and nuclear positioning, leading to smaller and abnormally shaped mutant plants.

This paper shows that a high-fat diet increases endometrial hyperplasia risk by reprogramming stromal fibroblasts to a pro-fibrotic state driven by estrogen.

This study shows that H2B variants, particularly H2B1O, alter chromatin accessibility and induce EMT in breast cancer, suggesting their role as onco-histones and potential therapeutic targets.

This study identifies an oxidase/reductase pair in Kratom that catalyzes the epimerization of 3S to 3R stereocenters in monoterpene indole alkaloids, enabling access to previously inaccessible compounds.

This study shows that H2B variants alter chromatin structure and oncogenic gene expression, suggesting they may be early cancer biomarkers and therapeutic targets.

This study develops a single-embryo metabolomics method to analyze metabolic and transcriptional changes in early Drosophila embryos with high temporal resolution.

The paper identifies CRIP1 as a novel surface marker for myometrial stem/progenitor cells using bulk and single-cell RNA-seq analyses.

This paper presents a single-embryo RNA-sequencing method to analyze early Drosophila gene expression, revealing transcription start times, degradation patterns, and sex-biased transcription.