Marie‐Hélène Verlhac

Elevated cortical tension triggers precocious ectopic polarization in mammalian oocytes, associated with lower developmental potential.

The paper shows that elevated cortical tension in mammalian oocytes causes early ectopic polarization, leading to developmental issues.

A novel RNP compartment boosts translation in growing mouse oocytes to avoid cytoplasm dilution

The paper identifies a novel RNP compartment in mouse oocytes that enhances translation to counteract cytoplasmic dilution during growth.

The post-transcriptional RNA splicing landscape driving oocyte division

This study defines the post-transcriptional RNA splicing landscape in fully grown mouse oocytes and identifies splicing events and regulatory programs essential for meiotic progression and oocyte division.

Atomic Force Microscopy reveals differences in mechanical properties linked to cortical structure in mouse and human oocytes

The paper uses Atomic Force Microscopy to analyze mechanical properties of mouse and human oocytes, showing differences in stiffness linked to cortical structure and maternal age effects.

Non-invasive characterization of oocyte deformability in micro-constrictions

This paper develops a microfluidic device to non-invasively measure mouse oocyte deformability, identifying elasticity as a key factor in mechanical health and potential for improved assisted reproduction.

An interpretable and versatile machine learning approach for oocyte phenotyping

This paper develops a machine learning framework for oocyte phenotyping using transmitted light images, identifying new features to assess maturation potential in mouse and human oocytes.

Separation and Loss of Centrioles from Primordidal Germ Cells to Mature Oocytes in the Mouse

The paper traces centriole loss in mouse oocytes from primordial germ cells to mature oocytes, showing centriole dissolution begins during follicular recruitment and meiotic resumption.