Elvira Nikalayevich

The paper shows that elevated cortical tension in mammalian oocytes causes early ectopic polarization, leading to developmental issues.

This study investigates separase inhibition and cohesin protection in oocytes, finding that cohesin is not protected early in meiosis I and at metaphase II arrest, and that kinetochore individualization in meiosis I is required for cohesin cleavage in meiosis II.

This paper develops a machine learning framework for oocyte phenotyping using transmitted light images, identifying new features to assess maturation potential in mouse and human oocytes.