Author

Kálmán Somogyi

German Cancer Research CenterORCID 0000-0001-8377-9766Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Rocı́o SotilloiD· 2 shared Alberto Diaz-JimeneziD· 1 shared Albrecht StenzingeriD· 1 shared Alicia Alonso de la VegaiD· 1 shared Benedikt BrorsiD· 1 shared Christopher W. MurrayiD· 1 shared Dmitri A. PetroviD· 1 shared Eli ReuveniiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Rocı́o SotilloORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedSep 23, 2025

EML4-ALK variant-specific genetic interactions shape lung tumorigenesis

Alberto Diaz-Jimenez, Emily G. Shuldiner, Kálmán Somogyi…·Rocı́o Sotillo

The paper investigates functional differences between EML4-ALK variants V1 and V3 in lung cancer using mouse models and human data, showing variant-specific effects on tumorigenesis.

8 citationstop 4%

mouseDNA methylation

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Molecular BiologybioRxivPreprintJun 1, 2022

Acute expression of human APOBEC3B in mice causes lethality associated with RNA editing

Alicia Alonso de la Vega, Nuri A. Temiz, Rafail Nikolaos Tasakis…·Rocı́o Sotillo

This study shows that overexpressing human APOBEC3B in mice causes lethality through RNA editing and organ dysfunction.

5 citations

mousebulk RNA-seq

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