Author

Adam E. Handel

John Radcliffe HospitalORCID 0000-0001-8385-6346Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Clive R. RosenthaliD· 2 shared Joseph H. Zhou· 2 shared Michael S. ZandiiD· 2 shared Thomas Arthur PollakiD· 2 shared Thomas D. MilleriD· 2 shared Alexander J. DaviesiD· 1 shared Alice L. Hickling· 1 shared Amir Khan· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Clive R. RosenthalORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 5, 2026

Spatial remodeling of the thymic stroma with age disrupts niches for T cell selection and tolerance

Andreas Tarcevski, Fatima Dhalla, Joshua W. Moore…·Georg A. Holländer

This study maps spatial changes in the aging mouse thymus, revealing stromal reorganization that disrupts T cell selection and tolerance.

DOI 10.64898/2026.07.29.741472

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 19, 2026

Sequential narrative binding by hippocampal CA2/3 sustains lifespan episodic detail retrieval

Thomas D. Miller, Joseph H. Zhou, Adam E. Handel…·Clive R. Rosenthal

This study shows that hippocampal CA2/3 damage causes time-invariant loss of episodic detail retrieval across adulthood, with specific impairments in local narrative coherence.

DOI 10.64898/2026.03.17.712337

humanstatistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 19, 2025

CA2/3-dependent stability of frontoparietal mnemonic representations predicts episodic deficits in human amnesia

Thomas D. Miller, Alice L. Hickling, Yan I. Wu…·Eleanor A. Maguire

This study shows that CA2/3 volume predicts mnemonic stability and episodic memory deficits in human amnesia using representational dissimilarity matrices.

DOI 10.1101/2025.02.19.638996

humanstatistical model

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 14, 2025

Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis

Bo Sun, Dominique Fernandes, Anne‐Kathrin Kienzler…·Sarosh R. Irani

2 citations

humanproteomics

𝕏 PostBluesky