Author

Jyothsna Girish

Johns Hopkins UniversityORCID 0000-0001-8392-1013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew S PekosziD· 1 shared Christa Han· 1 shared Heba H. MostafaiD· 1 shared Hisuan Liu· 1 shared Julie M. NortoniD· 1 shared Katherine FenstermacheriD· 1 shared Madeline YunkeriD· 1 shared Nicholas J. SwansoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Andrew S PekoszORCID

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1 paper

Recent·Most cited

Clade-defining mutations in human H1N1 hemagglutinin protein from 2021-2023 have opposing effects on in vitro fitness and antigenic drift

Nicholas J. Swanson, Jyothsna Girish, Madeline Yunker, Hisuan Liu, Julie M. Norton, Christa Han, Heba H. Mostafa, Katherine Fenstermacher, Richard Eric Rothman, Andrew S Pekosz

This study identifies clade-defining mutations in H1N1 hemagglutinin that improve viral fitness but reduce neutralization by vaccine-induced antibodies, revealing an evolutionary trade-off between replication and immune evasion.

bioRxiv · May 18, 2024 · PreprintMicrobiology