Author

Nicholas J. Swanson

Johns Hopkins UniversityORCID 0000-0002-5696-9967Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Andrew S PekosziD· 2 shared Christa Han· 1 shared David J. SullivaniD· 1 shared Eduardo AnayaiD· 1 shared Heba H. MostafaiD· 1 shared Hisuan Liu· 1 shared Jessica D. ResnickiD· 1 shared Julie M. NortoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Andrew S PekoszORCID

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2 papers

Recent·Most cited

Antibody Transcytosis and Neutralizing Activity in Respiratory Epithelial Cells

Eduardo Anaya, Yee Vue, Maggie Li, Jessica D. Resnick, Nicholas J. Swanson, David J. Sullivan, Andrew S Pekosz

This study investigates how IgG and IgA antibodies from serum are transported across respiratory epithelial cells and retain neutralizing activity against SARS-CoV-2 and influenza A virus.

bioRxiv · May 27, 2026 · PreprintMicrobiology

Clade-defining mutations in human H1N1 hemagglutinin protein from 2021-2023 have opposing effects on in vitro fitness and antigenic drift

Nicholas J. Swanson, Jyothsna Girish, Madeline Yunker, Hisuan Liu, Julie M. Norton, Christa Han, Heba H. Mostafa, Katherine Fenstermacher, Richard Eric Rothman, Andrew S Pekosz

This study identifies clade-defining mutations in H1N1 hemagglutinin that improve viral fitness but reduce neutralization by vaccine-induced antibodies, revealing an evolutionary trade-off between replication and immune evasion.

bioRxiv · May 18, 2024 · PreprintMicrobiology