Nadia Messaddeq

This study shows that TBPL2-dependent transcription is essential for maintaining cellular organization in growing oocytes by regulating RNA stability and decay machinery.

This study shows androgen receptor signaling maintains skeletal muscle stem cell quiescence and regenerative capacity, and its loss leads to premature activation and stem cell depletion.

This study identifies early systemic metabolic and organ dysfunction in SCA7 mice, highlighting peripheral contributions to disease pathogenesis.

This study shows BIN1 overexpression improves cardiac but not skeletal muscle function in Cav-3 knockout mice, highlighting tissue-specific therapeutic responses in caveolinopathies.

This study identifies LENT, a lncRNA regulated by MITF, which interacts with DHX36 to modulate translation and suppress autophagy in melanoma cells.

This study optimises C-protein-induced myositis by immunising mice with a specific C-protein polypeptide, resulting in a reproducible and stable model of inflammatory myopathy with key pathological features.