Irwin Davidson

This study identifies LENT, a lncRNA regulated by MITF, which interacts with DHX36 to modulate translation and suppress autophagy in melanoma cells.

This study identifies how TFE3 fusion proteins drive oxidative metabolism, ferroptosis resistance, and RNA synthesis in translocation renal cell carcinoma through genome-wide binding and multi-omics analyses.

This study shows novel synthetic ecteinascidins effectively treat melanoma by inhibiting super-enhancer-driven oncogenic transcription, even in resistant models.

The paper shows that activating β-catenin in Schwann-cell precursors during a specific developmental window promotes melanocyte specification over Schwann cell fate.