Author

Trisha Michel Wise-Draper

University of CincinnatiORCID 0000-0002-7279-4028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:proteomics· 1

Frequent Co-Authors

Maria A. LehniD· 2 shared Somchai ChutipongtanateiD· 2 shared Abdulaziz O. AlshwimiiD· 1 shared Ameet Ajit ChimoteiD· 1 shared Jay Bhati· 1 shared Laura ConfortiiD· 1 shared Leyla EsfandiariiD· 1 shared Manju Sharma· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Maria A. LehnORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Potassium channels mediate the inhibitory effect of exosomes on anti-tumor immunity in head and neck cancer

Ameet Ajit Chimote, Abdulaziz O. Alshwimi, Simran Venkatraman, Jay Bhati, Maria A. Lehn, Somchai Chutipongtanate, Sarmistha Das, Susan Kasper, Shesh Nath Rai, Scott M. Langevin, Trisha Michel Wise-Draper, Laura Conforti

This study identifies KCa3.1 channels as a target for enhancing immune responses in HNSCC by showing exosomes suppress CD8 T cell function through Ca2+ signaling disruption.

bioRxiv · Jul 25, 2025 · PreprintImmunology

Matrix stiffness modulated release of spheroid-derived extracellular vesicles and discovery of Piezo1 cargo

Maulee Sheth, Manju Sharma, Supasek Kongsomros, Maria A. Lehn, Takanori Takebe, Vinita Takiar, Trisha Michel Wise-Draper, Somchai Chutipongtanate, Leyla Esfandiari

This study shows that matrix stiffness modulates EV release and cargo from cancer spheroids, with stiff matrices promoting tumorigenic and metastatic profiles in EVs.

bioRxiv · Jan 13, 2025 · PreprintCancer Biology