Author

Sukanya Iyer

University of Massachusetts Chan Medical SchoolORCID 0000-0001-8409-235XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:CRISPR screen· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Allison M. KeeleriD· 2 shared Pengpeng LiuiD· 2 shared Scot A. WolfeiD· 2 shared Aamir MiriD· 1 shared Amanda A. Tutto· 1 shared Anya T. JoyntiD· 1 shared Ashley L. HarkinsiD· 1 shared Benjamin P. Roscoe· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Allison M. KeelerORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 12, 2025

Efficient Cas9 nuclease-based editing in skeletal muscle via lipid nanoparticle delivery

Sukanya Iyer, Katelyn Daman, Yehui Sun…·Scot A. Wolfe

SORT LNPs enable efficient Cas9-mediated repair of a pathogenic allele in skeletal muscle in a mouse model of LGMDR7.

3 citations

mouseCRISPR screen

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Genetic & Genomic MedicinemedRxivPreprintMay 7, 2025

Characterization of Immune Responses to rAAVrh8 Gene Therapy for GM2 Gangliosidosis in Phase 1/2 Trial

Terence R. Flotte, Meghan Blackwood, Motahareh Arjomandnejad…·Allison M. Keeler

This study characterizes immune responses to AAVrh8 gene therapy in CNS patients and evaluates the effectiveness of immunosuppression.

2 citations

humanexperimental assay

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Molecular BiologybioRxivPreprintDec 5, 2019

Efficient Homology-directed Repair with Circular ssDNA Donors

Sukanya Iyer, Aamir Mir, Joel Vega‐Badillo…·Scot A. Wolfe

This paper demonstrates that circular ssDNA donors improve HDR efficiency and reduce off-target integration compared to linear ssDNA donors in mammalian cells.

14 citations

humanCRISPR screen

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