Pharmacology & ToxicologybioRxivPreprint
Modulation of the agonist and antagonist activity of peptidic FPR1 ligands through N-terminal modifications: A structural and functional analysis
DOI 10.64898/2026.07.10.737841
Author
Denise Pajonczyk
University of MünsterORCID 0000-0001-8413-1646Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 shared papersPharmacology & Toxicology
Ursula RescherORCID
Mutual co-authors in cluster
3 papers
Recent·Most cited
- Pharmacology & ToxicologyBritish Journal of PharmacologyPeer-reviewed
Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profiles
Denise Pajonczyk, Merle F. Sternschulte, Oliver Soehnlein…·Ursula Rescher
The paper compares FPR1 and FPR2 signaling profiles using agonists, finding shared core signatures and low activity ratios for FPR2 agonists, challenging assumptions about receptor-specific inflammatory profiles.
11 citations - Systems BiologybioRxivPreprint
Physiological bias governs neutrophil inflammatory threat perception
Denise Pajonczyk, Lina Pauli, Charlotte Pünt…·Ursula Rescher
The paper shows that the cellular environment significantly affects GPCR signaling, leading to physiological bias in neutrophils that impacts drug efficacy.
2 citations