Author

Inès Leleu

Centre National de la Recherche ScientifiqueORCID 0000-0001-8414-8982Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

Sylviane PiediD· 2 shared Alain TedguiiD· 1 shared Capucine Picavet· 1 shared Céline AlbalaaiD· 1 shared Christoph J. BinderiD· 1 shared Corine GlineuriD· 1 shared David KlatzmanniD· 1 shared Fabien HerbertiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Sylviane PiedORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 15, 2026

Targeting IL-2 to inflamed tissues via oxidation-specific epitopes enables third-generation bispecific IL-2 therapeutics

Thomas Vazquez, Monica Cuevas-martinez, Nicolas Billiald…·David Klatzmann

This paper develops a third-generation IL-2 therapeutic that targets inflamed tissues via oxidation-specific epitopes, showing improved therapeutic benefit in multiple inflammation models.

DOI 10.64898/2026.09.10.750022

humanmouse

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 24, 2025

Astrocytes control the Neuroinflammation and ILC2 response through IL-33/ST2 signaling, during protection against Cerebral Malaria in Toxoplasma-P. berghei coinfected Mice

Inès Leleu, Tarun Keswani, Fabien Herbert…·Sylviane Pied

This study shows that Toxoplasma gondii brain infection protects against cerebral malaria in mice by altering astrocyte reactivity and activating the IL-33/ST2 pathway to recruit ILC2 cells.

DOI 10.1101/2025.10.24.684259

mouseexperimental assay

𝕏 PostBluesky