Author

Alain Tedgui

InsermORCID 0000-0002-7229-4875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ziad MallatiD· 2 shared Camille A. KnospiD· 1 shared Céline AlbalaaiD· 1 shared Charles CaëriD· 1 shared Christoph J. BinderiD· 1 shared Clément CochainiD· 1 shared Coraline HeroniD· 1 shared David KlatzmanniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Ziad MallatORCID

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2 papers

Recent·Most cited

Targeting IL-2 to inflamed tissues via oxidation-specific epitopes enables third-generation bispecific IL-2 therapeutics

Thomas Vazquez, Monica Cuevas-martinez, Nicolas Billiald, Florentina Porsch, Marie Sion, Fatima Saddouk, Céline Albalaa, Lorena Zentilin, Lauri Peil, Joan Teyra, Tahar Bouceba, Inès Leleu, Sylviane Pied, Mart Ustav, Alain Tedgui, , David Klatzmann

This paper develops a third-generation IL-2 therapeutic that targets inflamed tissues via oxidation-specific epitopes, showing improved therapeutic benefit in multiple inflammation models.

bioRxiv · Sep 15, 2026 · PreprintImmunology

Mucosal-Associated Invariant T Cells Promote Atherosclerosis Through Monocyte-Driven Inflammation

Tobias Radecke, Thomas Nipoti, Louise Z Wang, Nirmala Mouttoulingam, Marc Diedisheim, Mouna Chajadine, Emilie Bacquer, Coraline Heron, Paul Alayrac, Charles Caër, Ludivine Laurans, Camille A. Knosp, Pierre Liénart, Kenza Damache, Rida Al-Rifai, , Soraya Taleb

This study identifies MAIT cells as contributors to atherosclerosis through monocyte-driven inflammation, showing their enrichment in plaques and protective effects when depleted.

bioRxiv · Jan 21, 2026 · PreprintImmunology