Wade H. Berrettini

The paper analyzes single-nucleus RNA sequencing data from rat nucleus accumbens medium spiny neurons to identify transcriptomic subtypes and their potential roles in substance use disorders.

This paper conducts a multi-ancestry GWAS meta-analysis of suicide attempt, identifying 12 genome-wide significant loci and finding shared genetic risks with ADHD, smoking, and risk tolerance.

This study shows that bipolar disorder patient-derived neurons exhibit circadian rhythm abnormalities, with lithium non-responders showing more severe deficits that can be partially reversed by temperature entrainment.

This study identifies cell types associated with brain complex traits using GWAS and single-cell transcriptomics, revealing novel roles for oligodendrocytes in Parkinson's disease.

This study identifies 114 genome-wide significant loci for schizophrenia and bipolar disorder, with specific subphenotype associations and four genes distinguishing the disorders.