Author

Spyros Oikonomopoulos

McGill Genome CentreORCID 0000-0001-8446-765XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:long-read sequencing· 4 Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jiannis RagoussisiD· 4 shared Anthony BayegaiD· 3 shared Yu Chang Wang· 3 shared Kostas D. MathiopoulosiD· 2 shared Antonia Spanomitrou· 1 shared Antonis GiakountisiD· 1 shared Dimitris RallisiD· 1 shared Dionisia Mavritsakis· 1 shared

Activity by Year

2016-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersGenomics

Jiannis RagoussisORCID

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4 papers

Recent·Most cited

Long-read RNA-seq delineates temporal transcriptional dynamics in multiplexed and sexed single medfly embryos

Anthony Bayega, Spyros Oikonomopoulos, Dimitris Rallis, Dionisia Mavritsakis, Antonia Spanomitrou, Kostas D. Mathiopoulos, Jiannis Ragoussis

The paper uses long-read RNA-seq to analyze temporal transcriptional dynamics in single medfly embryos, identifying novel genes and developmental transitions.

bioRxiv · Oct 29, 2025 · PreprintGenomics

Improved Nanopore full-length cDNA sequencing by PCR-suppression

Anthony Bayega, Spyros Oikonomopoulos, Yu Chang Wang, Jiannis Ragoussis

The paper introduces a new Nanopore cDNA library preparation protocol that improves PCR efficiency and gene body coverage for full-length transcript sequencing.

Frontiers in Genetics · Oct 17, 2022Peer-reviewedGenomics

Transcriptome landscape of the developing olive fruit fly embryo delineated by Oxford Nanopore long-read RNA-Seq

Anthony Bayega, Spyros Oikonomopoulos, Maria‐Eleni Gregoriou, Konstantina T. Tsoumani, Antonis Giakountis, Yu Chang Wang, Kostas D. Mathiopoulos, Jiannis Ragoussis

This study uses Oxford Nanopore long-read RNA-Seq to characterize the transcriptome of the olive fruit fly embryo during early development, revealing novel genes and transcriptional dynamics.

Scientific Reports · Apr 12, 2021Peer-reviewedDevelopmental Biology

Benchmarking of the Oxford Nanopore MinION sequencing for quantitative and qualitative assessment of cDNA populations

Spyros Oikonomopoulos, Yu Chang Wang, Haig Djambazian, Dunarel Badescu, Jiannis Ragoussis

This study benchmarks the Oxford Nanopore MinION sequencing platform for quantifying and assessing the quality of cDNA populations using synthetic and complex samples.

bioRxiv · Apr 11, 2016Genomics