Kostas D. Mathiopoulos

Long-read RNA-seq delineates temporal transcriptional dynamics in multiplexed and sexed single medfly embryos

The paper uses long-read RNA-seq to analyze temporal transcriptional dynamics in single medfly embryos, identifying novel genes and developmental transitions.

Genome assembly of five Tephritid species for the enhancement of the Sterile Insect Technique

The paper presents chromosome-level genome assemblies for five Tephritid species using long-read sequencing, short-read polishing, and Hi-C scaffolding.

CRISPR/Cas9-mediated mutagenesis of the white-eye gene in the tephritid pest Bactrocera zonata

The paper develops a genetic tool for Bactrocera zonata by creating a chromosome-level genome and CRISPR/Cas9-induced white-eye mutants to aid in Genetic Sexing Strain development.

Detection of sex chromosomes in Tephritid pests using R-CQ and KAMY, two computational methods to enable species specific control.

The paper introduces two computational methods, R-CQ and KAMY, to detect sex chromosome sequences in Tephritid pests and evaluates their performance on chromosome-level assemblies.

A species-specific lncRNA modulates the reproductive ability of the Asian tiger mosquito

The paper identifies lncRNAs in the Asian tiger mosquito that regulate reproductive traits and shows their impact on fecundity and hatching rates.

Transcriptome landscape of the developing olive fruit fly embryo delineated by Oxford Nanopore long-read RNA-Seq

This study uses Oxford Nanopore long-read RNA-Seq to characterize the transcriptome of the olive fruit fly embryo during early development, revealing novel genes and transcriptional dynamics.

Decoding the reproductive system of the olive fruit fly, Bactrocera oleae

The paper analyzes the reproductive system of the olive fruit fly through transcriptomic and genomic studies, identifying genes involved in mating and potential targets for pest control.

De novo genome assembly of the olive fruit fly (Bactrocera oleae) developed through a combination of linked-reads and long-read technologies

The paper assembles the olive fruit fly genome using linked-reads and long-read technologies, achieving a highly contiguous Y-chromosome assembly.

Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests

The paper identifies a Y-linked gene, MoY, essential for male sex determination in medflies and shows its conservation across multiple fruit fly species, enabling potential genetic control strategies.