Author

Mariangela Kosmopoulou

National Centre of Scientific Research "Demokritos"ORCID 0000-0001-8454-5398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Athanasios SmyrnakisiD· 3 shared Dimitris K PapanastasiouiD· 3 shared Detlev SuckauiD· 2 shared Ajay JhaiD· 1 shared Albert J. R. HeckiD· 1 shared Alexander MakaroviD· 1 shared Christian AlbersiD· 1 shared Danique M.H. van RijswijckiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

Athanasios SmyrnakisORCID

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3 papers

Recent·Most cited

BiochemistryMolecular & Cellular ProteomicsPeer-reviewedAug 17, 2026

Top-down Sequencing of Intact Proteoforms using the timsOmni mass spectrometer: Accurate Determination of Co-occurring Histone Modifications

Francis Berthias, Nurgül Bilgin, Athanasios Smyrnakis…·Ole Nørregaard Jensen

This study uses multimodal mass spectrometry to accurately map co-occurring histone modifications on intact proteins, enabling residue-level assignment of modifications and positional isomers.

DOI 10.1016/j.mcpro.2026.101640

humanproteomics

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BiochemistrybioRxivPreprintOct 29, 2025

A prototype timsOmni platform enables confident annotation of key hypervariable regions of IgG immunoglobulins using low- and high-energy electron-based fragmentation.

Simon Ollivier, Dina Schuster, Danique M.H. van Rijswijck…·Albert J. R. Heck

1 citation

proteomicsexperimental assay

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Systems BiologybioRxivPreprintMay 15, 2023

Characterisation of an Omnitrap-Orbitrap platform equipped with IRMPD, UVPD and ExD for the analysis of peptides and proteins

Athanasios Smyrnakis, Nikita Levin, Mariangela Kosmopoulou…·Shabaz Mohammed

The paper characterizes an Omnitrap-Orbitrap mass spectrometer with multiple ion activation methods, showing its versatility in peptide and protein analysis.

DOI 10.1101/2023.05.15.540788

proteomicsexperimental assay

𝕏 PostBluesky