Christina Kiel

The paper calculates the spatio-temporal energy budget of the outer retina, showing higher ATP demand in rod-dominated areas at night and suggesting diurnal shifts in energy needs.

The paper estimates ATP production rates in the outer retina and examines how nutrient exchange and rod density change with age.

The paper predicts Ras-effector binding affinities using structural models and identifies mutations that alter binding energy, providing insights into rewiring Ras interactions.

The paper identifies context-specific KRAS-effectors in Caco-2 cells and shows that culture contexts have a larger impact on interaction rewiring than genetic contexts.

VarQ assesses the functional impact of single amino acid substitutions on protein activity, folding, and interactions using curated variants.