Cell BiologybioRxivPreprint
The Holliday junction resolvase GEN1 preserves genome integrity and self-renewal in mouse embryonic stem cells
Lucia Ramos-Lage, Cristina Ameneiro, David Martinez-Delgado…·Diana Guallar
This study shows that GEN1 is essential for mouse embryonic stem cell self-renewal and genome stability, with a non-enzymatic role in maintaining pluripotency.
DOI 10.64898/2026.07.23.740277