MicrobiologyCell Death and DifferentiationPeer-reviewed
The Mycobacterium tuberculosis ESX effector promotes pyroptosis-dependent pathogenicity and dissemination
Yajie Shen, Yifan He, Xuehe Liu…·Jixi Li
This study identifies EccB5 as a key Mtb effector that drives pyroptosis and enhances virulence by interacting with GSDMD and caspase-1.
DOI 10.1038/s41418-026-01895-3