Author

Xuehe Liu

Fudan UniversityPrimary ORCID profile (0000-0002-6033-0285 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Xuehe LiuiD1 paper · Fudan University

Biology Disciplines

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Neuroscience· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jixi LiiD· 3 shared Lu GengiD· 3 shared Jiasong Pan· 2 shared Yajie Shen· 2 shared Yifan DengiD· 2 shared Anke Chen· 1 shared Baocai Gao· 1 shared Bing XuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Jixi LiORCID

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Author profile →

3 papers

Recent·Most cited

The Mycobacterium tuberculosis ESX effector promotes pyroptosis-dependent pathogenicity and dissemination

Yajie Shen, Yifan He, Xuehe Liu, Anke Chen, Lu Geng, Xuehe Liu, Yuhui Gao, Yuxin Qiu, Lu Zhang, Zhidong Hu, Yicheng Sun, Sheng‐ce Tao, Xiao‐Yong Fan, Hua Yang, 戈宝学, , Jixi Li

This study identifies EccB5 as a key Mtb effector that drives pyroptosis and enhances virulence by interacting with GSDMD and caspase-1.

Cell Death and Differentiation · Oct 28, 2026Peer-reviewedMicrobiology

Gasdermin E couples mitochondrial damage to pyroptotic neurodegeneration in Parkinson disease

Jiasong Pan, Lu Geng, Xuehe Liu, Yinglei Wang, Ning Fang, Feiyan Xie, Yajie Shen, Yifan Deng, Yuyun Han, Suhua Li, Wenyong Xiong, Hua He, Ning‐Yi Shao, Jian Wang, Jixi Li

This paper identifies GSDME as a mediator of neurodegeneration in Parkinson's disease by linking mitochondrial damage to pyroptotic cell death through caspase-3 activation.

bioRxiv · Dec 16, 2025 · PreprintNeuroscience

Peptides alleviate cognitive impairment by inhibiting and disassembling amyloid-beta aggregates in Alzheimer disease

Wenqing Gao, Baocai Gao, Sen Wang, Di Wu, Pucheng Mei, Lu Geng, Chuhao Li, Yuanyuan Li, Xuehe Liu, Jiasong Pan, Jing Huang, Yifan Deng, Xiangjun Chen, Hexige Saiyin, Hongbo Yu, , Jixi Li

The paper shows that specific peptides inhibit Aβ aggregation and reduce cognitive impairment in Alzheimer's disease models.

bioRxiv · May 28, 2025 · PreprintNeuroscience