Bettina Schmid

Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis

This study shows that VPS18 mutations disrupt neutrophil maturation by impairing vesicle dynamics and autophagy, leading to neutropenia and recurrent infections.

SCAMP3 is essential for proper formation and function of neutrophil granules

The paper shows SCAMP3 is essential for neutrophil granule formation and function, with Scamp3-deficient neutrophils showing impaired bacterial killing in vitro.

Amyloid-beta precursor protein contributes to brain aging and learning decline

This study shows that amyloid-beta precursor protein contributes to non-pathological brain aging and learning decline in killifish and humans.

Myelin biogenesis is associated with pathological ultrastructure that is resolved by microglia during development

The paper investigates myelin structural changes during development in mice and zebrafish, finding that myelin degeneration is resolved by microglia, while sheath retractions occur independently.